The Josep Carreras Leukaemia Research Institute (IJC) is a non-profit research institute based in Barcelona dedicated to advancing the understanding of leukemia and related disorders, in collaboration with the University of Barcelona and the Autonomous University of Barcelona. The IJC has laboratories in 5 locations: i) Hospital Clínic, ii) Hospital de Sant Pau and iii) Hospital Germans Trias Pujol iv) Hospital del Mar and v) Hospital Josep Trueta Girona. IJC serves as a collaborative center for basic researchers and physicians to work together on fundamental clinical and biological aspects of leukemia. The IJC offers an excellent work environment based on a multidisciplinary fusion of state-of-the-art ideas and facilities.

We are looking for a POSTDOCTORAL RESEARCHER for the group lead by Dr. Gregoire Stik.

RESEARCH DESCRIPTION

The main interest of our lab is to understand the role of oncogenic fusion proteins induced by chromosomal translocations on chromatin organization and pathogenicity of leukemic cells. We combine and integrate multi-omics experimental and computational approaches encompassing state of the art technologies (chromatin conformation capture, NGS, genome editing, degron system, optogenetic) to elucidate the role of the chimeric protein on 3D chromatin organization and lymphoblastic malignancies. Understanding how translocation can affect biochemical properties of protein and alter the genome organization and the gene expression will offer potential new biomedical applications for the treatment of haematological malignancies. More information is available here.

WHAT WE NEED

• PhD in Biomedical Sciences or similar.
• Previous experience accomplishing tasks related with the job position.
• Experience in genomic research and related bioinformatics analysis.
• Postdoctoral experience outside of Spain is an important plus.
• You have excellent communication skills in English and can work independently.
• Organized, proactive, self-motivated, and enthusiastic.

WHAT WE OFFER

• 3-year contract
• Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute.
• The stimulating environment of the Barcelona metropolitan area.
• Full time contract.
• Competitive Salary to be further defined depending on candidate experience.
• The stimulating environment of the IJC and its scientific network.

DEADLINE FOR APPLICATIONS

To apply for this opportunity, please submit your application by March 31st, 2023

WHO ARE WE?

MISSION

The Josep Carreras Leukaemia Research Institute’ s mission is to carry out research into the epidemiological, preventive, clinical, translational, and basic aspects of cancer, with a special emphasis on Leukaemia and other malignant blood diseases, with the aim of finding a cure for these diseases through innovation.

VISION

The Josep Carreras Leukaemia Research Institute’ s vision is to be a world- renowned, multi-location research center of excellence that contributes towards improved outcomes and a cure for patients suffering from cancer, especially Leukaemia and other malignant blood diseases, through innovation, sustainability, social responsibility, talent, and professional expertise, and always caring for the environment.

For further information, please, visit our webpage: http://www.carrerasresearch.org/en and the Josep Carreras nonprofit organization: https://www.fcarreras.org/en

The European Commission awarded the IJC the HR Excellence seal (HRS4R) in July 2019. The HRS4R has the main objective of ensuring that research centres of excellence implement and respect the requirements of the European Charter for Researchers and the Code of Conduct for hiring researchers within their human resources policies.

This EC initiative aims to promote training, professional development, and mobility for all European scientists. The IJC supports these values and principles, which will not only serve to strengthen its internal policies but will actively stimulate excellent research and firmly situate the organization as an institution with a stimulating working environment that favours the development of its scientists.

IJC is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, and other legally protected characteristics.